Following a week of UEFA Champions League and Europa League fixtures, Premier League teams embark on a journey in the domestic campaign.
Liverpool and Chelsea will seek redemption after defeat in their respective European competitions with the Premiership entering matchday 6.
Here are the weekend fixtures:
FRIDAY, SEPTEMBER 20
Southampton v AFC Bournemouth – 21:00
SATURDAY, SEPTEMBER 21
Leicester City v Tottenham – 13:30
Manchester City v Watford – 16:00
Everton v Sheffield United – 16:00
Burnley v Norwich City – 16:00
Newcastle United v Brighton – 18:30
SUNDAY, SEPTEMBER 22
West Ham United v Manchester United – 15:00
Crystal Palace v Wolves – 15:00
Arsenal v Aston Villa – 17:30
Chelsea v Liverpool – 17:30
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